Gholamhossein Kazemian; Gholamhossein Kazemian; Reza Tavakoli Darestani; Alireza Manafi Rasi; Mohammad Mahdi Sarzaeem; Ramin Farhang Zanganeh; Arash Ghaffari; Farshad Safdari
Abstract
Osteosarcoma is the most common malignant tumor of bone in young people. We report a case of recurrent post-radiation osteogenic sarcoma in the clavicle of a 28-year-old man with a history of Hodgkin’s lymphoma.
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Osteosarcoma is the most common malignant tumor of bone in young people. We report a case of recurrent post-radiation osteogenic sarcoma in the clavicle of a 28-year-old man with a history of Hodgkin’s lymphoma.
Seyyed Morteza Kazemi, MD; Seyed Mehdi Hosseini Khameneh, MD; Siavash Hemati Islamloo, MD; Ramin Farhang Zanganeh, MD; Mohammad Reza Bigdeli, MD; Seyyed Mohammad Ghoreishi, MD
Abstract
Background: Prior to 1980 decade, surgical ideas and facts were mainly based on the individual surgeon’s experience and the collective judgment of groups of surgeons. In the 1980’s the concept of “Evidence Based Medicine” became popular suggesting that all surgical practices must be based on ...
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Background: Prior to 1980 decade, surgical ideas and facts were mainly based on the individual surgeon’s experience and the collective judgment of groups of surgeons. In the 1980’s the concept of “Evidence Based Medicine” became popular suggesting that all surgical practices must be based on evidence and not experience. According to the widespread publication of medical articles nowadays, the question often arises about the dependability and strength of the evidence. We are reporting the level of evidence (LOE) of articles published in the Journal of the Iranian Orthopaedic Association between 1995 and 2008. Methods: All the articles published in the Iranian Journal of Orthopaedic Surgery (1995-2008) were studied separately by 5 groups of physicians. The level of evidence rating system was based on the Journal of Bone and Joint Surgery, which classifies articles into therapeutic, prognostic, diagnostic and economic subgroups. The articles are subsequently divided into five levels in accordance with the defined levels of evidence.Results: Over half of the articles (54%) were therapeutic, 9% diagnostic, 35% prognostic and 2% economic. Overall 2% were placed as level I, 8% level II, 5% level III, 84% level IV and 1% level V.Conclusion: Therapeutic and prognostic articles and evidence level IV were the most common types observable in the articles published in the Iranian Journal of Orthopaedic Surgery. Furthermore, level I to III articles in this journal had increased over 3.5 times between 1995 and 2008.
Faramarz Mosaffa, MD; Seyyed Morteza Kazemi, MD; Mohammad Kaffashi, MD; Alireza Eajazi, MD; Laleh Daftari Besheli, MD; Mohammad Reza Bigdeli, MD; Ramin Farhang Zanganeh, MD
Abstract
Background: Antifibrinolytic drugs are used to minimize the potential risks of bleeding and blood transfusion. Studies showed the effect of tranexamic acid on decreasing blood loss in cemented THA. We would like to report its effect on cementless hip arthroplasty.Methods: A prospective double blind randomized ...
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Background: Antifibrinolytic drugs are used to minimize the potential risks of bleeding and blood transfusion. Studies showed the effect of tranexamic acid on decreasing blood loss in cemented THA. We would like to report its effect on cementless hip arthroplasty.Methods: A prospective double blind randomized controlled study was conducted on 64 candidates for cementless THA under epidural anesthesia between 2006 and 2008. The patients were randomly divided into study and control groups. 32 patients received tranexamic acid (15 mg/kg) and 32 received normal saline immediately before surgery.Results: The comparison of two groups showed less drop in 6 hour (p < /em>=0.035) and 24 hour (p < /em>=0.043) post-operative hemoglobin levels, less intra-operative bleeding (p < /em>=0.024), and less need for allogenic blood transfusion (p < /em>=0.017) in the tranexamic acid group. Although the mean of 6 and 24 hour hematocrit level was higher and hospital stay was shorter in the tranexamic acid group, but the differences were not significant.Conclusion: administration of tranexamic acid before cementless THA under epidural anesthesia can reduce intra-operative and post-operative bleeding as well as need for blood transfusion.
